Pediatric Sarcoma

Major Types of Soft Tissue Sarcomas in Children

Tissue of Origin	Types of Cancer	Usual Location in the Body	Most Common Ages
Muscle
Striated muscle	Rhabdomyosarcoma
	Embryonal	Head and neck, genitourinary tract	Infant–4
	Alveolar	Arms, legs, head and neck	Infant–19
Smooth muscle	Leiomyosarcoma	Trunk	15-19
Fibrous tissue	Fibrosarcoma	Arms and legs	15-29
	Malignant fibrous	Legs	15–19
Fat	Liposarcoma	Arms and legs	15–19
Blood vessels	Infantile hemangio-pericytoma	Arms, legs, trunk, head, and neck	Infant–4
Synovial tissue (linings of joint cavities, tendon sheaths)	Synovial sarcoma	Legs, arms, and trunk	15–19
Peripheral nerves	Malignant peripheral nerve sheath tumors (also called neurofibrosarcomas, malignant schwannomas and neurogenic sarcomas)	Arms, legs, and trunk	15–19
Muscular nerves	Alveolar soft part sarcoma	Arms and legs	Infant-19
Cartilage and bone-forming tissue	Extraskeletal myxoid chondrosarcoma	Legs	10–14
	Extraskeletal mesenchymal	Legs	10–14